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Data from: Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense

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posted on 2024-11-08, 19:33 authored by Megan C. Mears, ABHIJEET BAKREABHIJEET BAKRE

This dataset accompanies manuscript "Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense" published in the journal Viruses on 11/07/2024. In this manuscript, the authors identified regions in the genome of Orthoavulavirus javaense, the causative of Newcastle disease that can modify function of host microRNAs. They postulate that viral sequences can either mimic host microRNA activity (viral seed mimics) or inhibit (viral seed sponges) it via sequence dependent sequestration. The data suggest that virulent "velogenic" strains of the virus harbor more viral seed mimics vs lentogenic viral genomes that harbor more sponges. The excel file contains tables showing the original BLASTN hits, the shortlisted viral seed mimics and seed sponges and individual tables for viral gene and intergenic region specific hits. The workbook also contains summaries of all the data finally graphed in the manuscript online as well as a list of all accession numbers used in the analysis.

The sequences used in these analyses were obtained from NCBI nucleotide and represent full length genomes corresponding to the different pathotypes of NDV.

Funding

USDA-ARS: 6040-32000-082-00D

History

Data contact name

Bakre Abhijeet A.

Data contact email

abhijeet.bakre@usda.gov

Publisher

Ag Data Commons

Intended use

The dataset provides the manuscript and all the background data used to generate conclusions drawn in the manuscript.

Use limitations

None

Temporal Extent Start Date

2022-05-01

Temporal Extent End Date

2024-11-07

Frequency

  • notPlanned

Theme

  • Non-geospatial

ISO Topic Category

  • farming
  • biota

OMB Bureau Code

  • 005:18 - Agricultural Research Service

OMB Program Code

  • 005:040 - National Research

ARS National Program Number

  • 103

ARIS Log Number

000398489

Pending citation

  • No

Related material without URL

microRNA; viruses; Orthoavulavirus; data collection; genome; Newcastle disease; virulence

Public Access Level

  • Public