Data from: Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense
This dataset accompanies manuscript "Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense" published in the journal Viruses on 11/07/2024. In this manuscript, the authors identified regions in the genome of Orthoavulavirus javaense, the causative of Newcastle disease that can modify function of host microRNAs. They postulate that viral sequences can either mimic host microRNA activity (viral seed mimics) or inhibit (viral seed sponges) it via sequence dependent sequestration. The data suggest that virulent "velogenic" strains of the virus harbor more viral seed mimics vs lentogenic viral genomes that harbor more sponges. The excel file contains tables showing the original BLASTN hits, the shortlisted viral seed mimics and seed sponges and individual tables for viral gene and intergenic region specific hits. The workbook also contains summaries of all the data finally graphed in the manuscript online as well as a list of all accession numbers used in the analysis.
The sequences used in these analyses were obtained from NCBI nucleotide and represent full length genomes corresponding to the different pathotypes of NDV.
Funding
USDA-ARS: 6040-32000-082-00D
History
Data contact name
Bakre Abhijeet A.Data contact email
abhijeet.bakre@usda.govPublisher
Ag Data CommonsIntended use
The dataset provides the manuscript and all the background data used to generate conclusions drawn in the manuscript.Use limitations
NoneTemporal Extent Start Date
2022-05-01Temporal Extent End Date
2024-11-07Frequency
- notPlanned
Theme
- Non-geospatial
ISO Topic Category
- farming
- biota
OMB Bureau Code
- 005:18 - Agricultural Research Service
OMB Program Code
- 005:040 - National Research
ARS National Program Number
- 103
ARIS Log Number
000398489Pending citation
- No
Related material without URL
microRNA; viruses; Orthoavulavirus; data collection; genome; Newcastle disease; virulencePublic Access Level
- Public