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Ulcerative Colitis but not DSS induced colitis associated microbiota induces early colitis onset in IL-10 -/- mice

dataset
posted on 2024-06-11, 07:27 authored by Purdue University
The goal of the study was to determine if mice genetically susceptible to colitis are colonized with colitic-associated bacteria, will they exhibit an early onset and increased disease severity of colitis. The results of the study provide evidence for the use of fecal microbial transplantations from individuals with colitis to model the progression and severity of colitis in IL-10 -/- mice. Furthermore, the results of the study indicate that microbial stability is influential in disease progression.

Funding

U.S. Department of Agriculture, 2019-67017-29258

U.S. Department of Agriculture, 2022-67017-37184

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2024-04-25

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

sequence analysis

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA1104649

Preferred dataset citation

It is recommended to cite the accession numbers that are assigned to data submissions, e.g. the GenBank, WGS or SRA accession numbers. If individual BioProjects need to be referenced, state that "The data have been deposited with links to BioProject accession number PRJNA1104649 in the NCBI BioProject database (https://www.ncbi.nlm.nih.gov/bioproject/)."

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