Type 4 resistant potato starch alters the microbiome, colon and cecal gene expression, and resistance to Citrobacter rodentium infection in mice fed a Total Western Diet

dataset

posted on 2025-04-26, 03:57 authored by USDA ARS

Mice were fed a Total Western Diet based on the National Health and Nutrition Examination Survey (NHANES) 50th percentile intake levels for Americans supplemented with 0, 2, 5 or 10% type 4 resistant potato starch before being infected with Citrobacter rodentium to induce bacterial colitis. Changes in the cecal microbiome were investigated using 16S sequencing, and changes in cecum and distal colon gene expression were evaluated using RNASeq analysis.

Funding

USDA: 8040-53000-021-000-D

History

Data contact name

BioProject Curation Staff

Data contact email

bioprojecthelp@ncbi.nlm.nih.gov

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2024-07-29

Theme

Non-geospatial

ISO Topic Category

biota

National Agricultural Library Thesaurus terms

sequence analysis

Pending citation

Public Access Level

Public

Accession Number

PRJNA1141498

Preferred dataset citation

It is recommended to cite the accession numbers that are assigned to data submissions, e.g. the GenBank, WGS or SRA accession numbers. If individual BioProjects need to be referenced, state that "The data have been deposited with links to BioProject accession number PRJNA1141498 in the NCBI BioProject database (https://www.ncbi.nlm.nih.gov/bioproject/)."