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Transcriptomic differences in livers from pubertal mice fed the AIN93G standard diet or a high-fat diet

dataset
posted on 2024-01-27, 05:13 authored by USDA- Grand Forks Human Nutrition Research Center
The analyses show that consumption of a high-fat diet, compared to a standard control diet, alters hepatic transcriptome in pubertal mice. Overall design: Weanling three-week-old female C57BL/6 mice were randomly assigned into two groups and fed the AIN93G standard diet (providing 16% of energy from soybean oil) or a high-fat diet (a modified AIN93 formulation providing 45% of energy from soybean oil) for three weeks. At termination, mice were euthanized every four hours followed by exsanguination for a period of 48 hours. Livers were collected and stored at -80°C for designed analyses. Only samples from the first 24-hour cycle were used for the RNA-seq analysis.

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2022-11-28

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

transcriptome; gene expression

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA906151

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