Simultaneous Transcriptome Profiles of Human Pathogenic Bacteria and Leaves of Arabidopsis and Lettuce

We aimed to simultaneously obtain the transcriptomic profiles of the two human pathogenic bacteria most frequently linked to produce outbreaks, Salmonella and E. coli, with the model plant Arabidopsis and the vegetable crop lettuce. The dual RNA-seq analysis conducted here enabled us to exhibit the shared and separate biological processes of bacterial- and plant-species modulated during this interaction. In addition, we identified multiple bacterial and plant genes with potential key roles in the leaf colonization by these two human pathogenic bacteria.