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Rhipicephalus microplushemocyte innate cellular and humoral immune responses to babesialinfection

dataset
posted on 2024-02-06, 23:49 authored by USDA ARS Animal Disease Research Unit
To understand the effect of Babesia infection on Rhipicephalus microplus hemocyte gene expression, we performed high throughput RNA-sequencing using samples collected from Rhipicephalus microplus uninfected tick hemolymph and infected with either Babesia bigemina or Babesia bovis. We evaluated gene expression differences that may be attributed to tick immune defense to babesial infection. Overall design: Parasite mRNA isolated from 3 biological replicates for each of 1) uninfected tick hemolymph, 2) Babesia bigemina kinete stage parasites from infected tick hemolymph, and 3) Babesia bovis kinete stage parasites from infected tick hemolymph, were compared by RNAseq methodology using Illumina technology.

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2023-09-18

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

transcriptome; gene expression

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA1018599

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