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Raw Sequence Reads of Mannheimia haemolytica Isolates From Cattle

posted on 2024-06-11, 07:10 authored by USDA/ARS
Mannheimia haemolytica are bacteria that typically reside in cattle as commensal members of their upper respiratory tract. However, when cattle are immunocompromised, M. haemolytica can invade their lungs and cause respiratory disease and/or death. It has been known for some time that not all strains of M. haemolytica associate equally with bovine respiratory disease. This has been shown by both serotype and pulsed-field gel electrophoresis (PFGE) typing methods. In this study, the genomes of 1,133 M. haemolytica isolates were sequenced, including isolates from the lungs of cattle with respiratory disease and from the nasopharynx of cattle without signs of respiratory disease. A new classification system for M. haemolytica of North American cattle was developed from analyses of the sequences and identification of nucleotide polymorphism genotypes. Additionally, associations of select genetic types of M. haemolytica with the lungs of cattle with respiratory disease, a distinct integrative and conjugative element (ICE), and antibiotic resistance genes were identified.


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BioProject Curation Staff


National Center for Biotechnology Information

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  • Non-geospatial

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  • biota

National Agricultural Library Thesaurus terms

sequence analysis

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  • No

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  • Public

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It is recommended to cite the accession numbers that are assigned to data submissions, e.g. the GenBank, WGS or SRA accession numbers. If individual BioProjects need to be referenced, state that "The data have been deposited with links to BioProject accession number PRJNA326933 in the NCBI BioProject database ("

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