Downy mildew (Peronospora effusa) causes significant economic losses in spinach, especially to the organic sector of the industry where the use of synthetic fungicides is not allowed for disease control. In this study, we conducted RNA-seq analyses of transcriptomic changes in leaf tissue of resistant and susceptible spinach cultivars Solomon and Viroflay, respectively, at an early stage of pathogen establishment (48 hours post inoculation, hpi) to a late stage of symptom expression and pathogen sporulation (168 hpi). The overall objective of this study was to investigate the molecular mechanism of spinach- P. effusa interactions and candidate genes for resistance against infection.
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