Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus
dataset
posted on 2023-12-19, 16:02 authored by Giovana Ciacci Zanella, Celeste A. Snyder, Bailey Arruda, Kristin Whitworth, Bhanu Telugu, Amy L. BakerAn experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs.
Resources in this dataset:
- Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus File Name: TMPRSS2 dataset.xlsx Resource Description: Supporting data for: Nasal shedding of A/swine/Iowa/A02524480/2020 (IA/20) H1N1 by virus titration on cell culture or qRT-PCR; Infection of IA/20 H1N1 in WT and TMPRSS2-/- pigs; Immunohistochemical (IHC) staining of Influenza A virus nucleoprotein; Cytokine and chemokine panel performed on bronchioalveolar lavage fluid.
Funding
USDA-NIFA: 2015-67015-22845
USDA-ARS: 5030-32000-231-000-D
History
Data contact name
Baker, Amy L.Data contact email
amy.l.baker@usda.govPublisher
Ag Data CommonsTemporal Extent Start Date
2022-10-01Temporal Extent End Date
2023-05-31Theme
- Not specified
Geographic Coverage
{"type":"FeatureCollection","features":[{"geometry":{"type":"Point","coordinates":[-93.617248535156,42.044002396934]},"type":"Feature","properties":{}}]}Geographic location - description
Ames, IowaISO Topic Category
- farming
- health
National Agricultural Library Thesaurus terms
swine; lungs; inflammation; Influenza A virus; swine diseases; disease resistance; nose; Iowa; viruses; titration; cell culture; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; immunohistochemistry; staining; nucleoproteins; chemokinesOMB Bureau Code
- 005:18 - Agricultural Research Service
OMB Program Code
- 005:040 - National Research
ARS National Program Number
- 103
Pending citation
- No
Public Access Level
- Public