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TMPRSS2 dataset.xlsx (18.54 kB)

Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus

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posted on 2023-12-19, 16:02 authored by Giovana Ciacci Zanella, Celeste A. Snyder, Bailey Arruda, Kristin Whitworth, Bhanu Telugu, Amy L. Baker

An experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs.

Resources in this dataset:

  • Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus File Name: TMPRSS2 dataset.xlsx Resource Description: Supporting data for: Nasal shedding of A/swine/Iowa/A02524480/2020 (IA/20) H1N1 by virus titration on cell culture or qRT-PCR; Infection of IA/20 H1N1 in WT and TMPRSS2-/- pigs; Immunohistochemical (IHC) staining of Influenza A virus nucleoprotein; Cytokine and chemokine panel performed on bronchioalveolar lavage fluid.

Funding

USDA-NIFA: 2015-67015-22845

USDA-ARS: 5030-32000-231-000-D

History

Data contact name

Baker, Amy L.

Data contact email

amy.l.baker@usda.gov

Publisher

Ag Data Commons

Temporal Extent Start Date

2022-10-01

Temporal Extent End Date

2023-05-31

Theme

  • Not specified

Geographic Coverage

{"type":"FeatureCollection","features":[{"geometry":{"type":"Point","coordinates":[-93.617248535156,42.044002396934]},"type":"Feature","properties":{}}]}

Geographic location - description

Ames, Iowa

ISO Topic Category

  • farming
  • health

National Agricultural Library Thesaurus terms

swine; lungs; inflammation; Influenza A virus; swine diseases; disease resistance; nose; Iowa; viruses; titration; cell culture; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; immunohistochemistry; staining; nucleoproteins; chemokines

OMB Bureau Code

  • 005:18 - Agricultural Research Service

OMB Program Code

  • 005:040 - National Research

ARS National Program Number

  • 103

Pending citation

  • No

Public Access Level

  • Public

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