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Parental cardiorespiratory fitness influences early life energetics and metabolic health

dataset
posted on 2024-06-11, 07:30 authored by Arkansas Children's Nutrition Center
Introduction. High cardiorespiratory fitness (CRF) is associated with a reduced risk for metabolic disease across the life course. Evidence suggests this may partly be due to superior mitochondrial respiratory function. Objective. To determine the impact of intrinsic CRF on bioenergetics and metabolic health in adulthood and early life. Methods. Adult rats selectively bred for low (low-capacity runners, LCR) and high (high-capacity runners, HCR) running capacity were metabolically phenotyped prior to being mated. Thereafter, LCR and HCR weanlings were studied at 4-6 weeks of age. Microbial abundance of weanlings' colon content was evaluated by 16S rRNA sequencing.

Funding

U.S. Department of Agriculture, 60626-51000-012-06S

National Institute of General Medical Sciences, P20GM109096

National Institute of General Medical Sciences, R35GM142744

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2023-05-22

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

sequence analysis

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA975204

Preferred dataset citation

It is recommended to cite the accession numbers that are assigned to data submissions, e.g. the GenBank, WGS or SRA accession numbers. If individual BioProjects need to be referenced, state that "The data have been deposited with links to BioProject accession number PRJNA975204 in the NCBI BioProject database (https://www.ncbi.nlm.nih.gov/bioproject/)."

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