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Overexpression of the Elongator complex subunit 4 in Arabidopsis

dataset
posted on 2024-01-26, 23:54 authored by University of Florida
The goal of the project is to study the effect of overexpression of the Elongator complex subunit 4 (ELP4) on the epigenome of Arabidopsis. Elongator has been shown to have histone acetyltransferase activity and be involved in DNA demethylation. In this study, the ELP4 gene driven by the constitutive cauliflower mosaic virus 35S promoter was transformed into the Arabidopsis accession Landsberg erecta (Ler). Epigenomes of the 35S:ELP4 (ELP4OE) transgenic line and the wild-type Ler were analyzed by bisulfite sequencing. Results show that overexpression of ELP4 significantly altered the genome-wide DNA methylation landscape in Arabidopsis.

Funding

National Science Foundation, PBI1758932

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2020-04-27

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

sequence analysis

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA628652

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