Ag Data Commons
OGSv2.2.tar.gz (4.23 MB)

Manduca sexta Official Gene Set v2.2

Download (4.23 MB)
posted on 2024-02-16, 18:18 authored by Michael KanostMichael Kanost, Gary Blissard, Stephen Richards, Susan Brown, Alexie Papanicolaou, Nicolae Herndon, Haobo Jiang

Manduca sexta, known as the tobacco hornworm or Carolina sphinx moth, is a lepidopteran insect that is used extensively as a model system for research in insect biochemistry, physiology, neurobiology, development, and immunity. One important benefit of this species as an experimental model is its extremely large size, reaching more than 10 g in the larval stage. M. sexta larvae feed on solanaceous plants and thus must tolerate a substantial challenge from plant allelochemicals, including nicotine.

This dataset presents the Manduca sexta Official Gene Set (OGS) v2.2. It is derived from Official Gene Sets OGSv2.0 and OGSv2.1. OGSv2.0 was modified to meet NCBI-GenBank quality review, resulting in OGSv2.1. This was deposited in NCBI GenBank (accession number AIXA00000000). OGS2.1 was lifted over to assembly JHU_Msex_v1.0/GCF_014839805.1 using the LiftOff ( and Genometools ( software, resulting in OGSv2.2. OGSv2.2 has quality issues due to the liftover - the i5k Workspace@NAL recommends NCBI Annotation Release 102 for general analysis, instead.

Resources in this dataset:

  • Resource Title: Manduca sexta Official Gene Set v2.2.

    File Name: OGSv2.2.tar.gz

    Resource Description: The attached tar.gz archive (OGSv2.2.tar.gz) contains the following files:

    mansex_OGSv2.2.gff. Gff3 file of all gene predictions of Manduca sexta genome annotations OGSv2.2 readme.txt. A readme describing the OGS generation process.


National Institutes of Health: GM041247

Defense Advanced Research Projects Agency


Data contact name

Kanost, Michael

Data contact email


Ag Data Commons

Intended use

This genome sequence, annotation, and analysis provide an important new resource from a well-studied model insect species and will facilitate further biochemical and mechanistic experimental studies of many biological systems in insects.

Temporal Extent Start Date


Temporal Extent End Date



  • Not specified

Geographic Coverage


ISO Topic Category

  • biota

Ag Data Commons Group

  • Insects - i5K

National Agricultural Library Thesaurus terms

genomics; genes; prediction; genome assembly; sequence analysis; genome; Manduca sexta; insects; models; insect biochemistry; immunity; insect larvae; allelochemicals; nicotine; tissues; gene expression regulation; apoptosis; vacuoles; exoskeleton; egg shell; muscles; vision; ion channels; signal transduction; neuropeptides; neurotransmitters; lipid metabolism

Primary article PubAg Handle

Pending citation

  • No

Public Access Level

  • Public

Preferred dataset citation

Kanost, Michael R.; Blissard, Gary; Richards, Stephen; Brown, Susan; Papanicolaou, Alexie; Herndon, Nicolae; Jiang, Haobo (2021). Manduca sexta Official Gene Set v2.2. Ag Data Commons.

Usage metrics


    Ref. manager