Escherichia coli strain:R1 Genome sequencing

Pathogenic E. coli strains that carry multiple virulence determinants such as cytotoxic necrotizing factors (CNFs), hemolysins (Hlys), and fimbrial adhesins are responsible for various diseases of humans and animals. These virulence factors are usually encoded by plasmids. E. coli R1, which was isolated from a calf with diarrhea, carry multiple toxin genes including CNF and hemolysins. The interactions between these bacterial toxins produced by E. coli R1 and various mammalian cells are of our research interests.