Dietary Phytochemicals Modulate the Gut-Vascular Axis Through Microbiome-Metabolome Interaction

Gut microbes metabolize dietary phytonutrients and influence their biological effects through diet-derived microbial metabolites. However, significant gaps in knowledge remain regarding whether dietary phytochemicals provide vascular benefits via microbiome-metabolome interaction. We address this gap by using dietary blueberries as a model and employing germ-free mice and antibiotic-treated mice.