posted on 2023-12-18, 20:08authored byErica Spackman, Mary J. Pantin-Jackwood, Scott A. Lee, Diann Prosser
<p>Treatment groups of ducks were exposed to different virus doses (2, 4, 6 log10 50% egg infectious doses) and by different routes (contact or intrachoanal). The experimental setting was a laboratory with animal care as approved by the institutional animal care and use committee as appropriate for the species and age of bird. Data are the virus titers shed by the oral and cloacal route for individual mallard ducks exposed to H5N1 highly pathogenic avian influenza virus by day post exposure. Samples were collected through 11 days post exposure. Virus titer equivalents were determined by quantitative real-time RT-PCR. Serological data are serum antibody titers to the challenge virus as determined by hemagglutination inhibition assay (reciprocal of the log2 dilution) determined with serum collected 10 or 11 days post exposure. </p><div><br>Resources in this dataset:</div><br><ul><li><p>Resource Title: Virus_shed_data.</p> <p>File Name: Spackman_et_al_virus_shedData from H5_mallard_study_2022.csv</p><p>Resource Description: Virus shed data determined by quantitative real-time RT-PCR</p></li><br><li><p>Resource Title: Serology data for H5 challenged mallards.</p> <p>File Name: Spackman_et_al_Serology_Data from H5_mallard_study_2022.csv</p><p>Resource Description: Serology determined by hemagglutination inhibition assay. NS= no serum (sample not run)</p></li></ul><p></p>
A full description of the methods is presented in the associated publication. Data from individual animals reported in the peer-reviewed publication. May be useful for meta-analyses.
pathogenesis; Influenza A virus; Anas platyrhynchos; ducks; viruses; viral load; blood serum; avian influenza
OMB Bureau Code
005:18 - Agricultural Research Service
OMB Program Code
005:040 - National Research
ARS National Program Number
103
Pending citation
No
Related material without URL
Spackman et al. The pathogenesis of a 2022 North American highly pathogenic clade 2.3.4.4b H5N1 avian influenza virus in mallards (Anas platyrhynchos). Journal: submitted, 2023. Full citation not available yet.
Public Access Level
Public
Preferred dataset citation
Spackman, Erica; Pantin-Jackwood, Mary J.; Lee, Scott A.; Prosser, Diann (2023). Data from: The pathogenesis of a 2022 North American highly pathogenic clade 2.3.4.4b H5N1 avian influenza virus in mallards (Anas platyrhynchos). Ag Data Commons. https://doi.org/10.15482/USDA.ADC/1528399