Data from: Microarray analysis of subcutaneous adipose tissue from mature cows with divergent body weight gain after feed restriction and realimentation
Body weight response to periods of feed restriction and realimentation is critical and relevant to the agricultural industry. The purpose of this study was to evaluate differentially expressed genes identified in subcutaneous adipose tissue collected from cows divergent in body weight (BW) gain after feed restriction and realimentation. We compared adipose samples from cows with greater gain based on average daily gain (ADG) during realimentation with samples from cows with lesser gain. Specifically, there were four comparisons including two comparing the high and low gain animals across each feeding period (feed restriction and realimentation) and two that compared differences in feed restriction and realimentation across high or low gain classifications. Using microarray analysis, we provide a set of differentially expressed genes identified between the high and low gain at both periods of nutrient restriction and realimentation. These data identify multiple differentially expressed genes between these two phenotypes across both nutritional environments.
Resources in this dataset:
Resource Title: NCBI Gene Expression Omnibus (GEO) Accession GSE94746 Display .
File Name: Web Page, url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE94746
Evaluation of the naturally occurring transcriptome variation among beef cows with divergent gain.
Funding
USDA-ARS
History
Data contact name
Lindholm-Perry, Amanda K.Data contact email
Amanda.Lindholm@ars.usda.govPublisher
Data in BriefIntended use
Identifying gene networks and metabolic pathways potentially involved in the divergence of weight gain may provide a platform for further investigation into some of the critical control points of feed efficiency. Adipose tissue is a highly metabolically active tissue and also is closely regulated by energetics of the animal. Gene networks identified in this tissue may provide insight into how, during extreme energy balance times, animals divergent in body weight gain respond and adjust to these nutritional extremes. Differentially expressed genes and pathways identified in these comparisons may be used in future experiments investigating response in adipose tissue to nutritional status and divergence in feed efficiency. Datasets evaluating the molecular mechanisms of feed restriction and realimentation in cattle are scarce; thus, these data may be useful for inclusion with additional sets of similar data for a meta-analysis of nutritional treatments.Theme
- Not specified
ISO Topic Category
- biota
- farming
National Agricultural Library Thesaurus terms
body weight; restricted feeding; repletion; agricultural industry; genes; adipose tissue; cows; average daily gain; microarray technology; phenotype; transcriptome; subcutaneous fat; beef cowsOMB Bureau Code
- 005:18 - Agricultural Research Service
OMB Program Code
- 005:040 - National Research
Primary article PubAg Handle
Pending citation
- No
Public Access Level
- Public