posted on 2024-06-25, 20:10authored byAdrienne NarroweAdrienne Narrowe, LinShu Liu, Karley K. Mahalak, Jamshed T. Bobokalonov, Jenni Firrman, Johanna Lemons, Kyle Bittinger, Weiming Hu, Steven M. Jones, Ahmed M. Moustafa
The SHIME® (Simulator of the Human Intestinal Microbial Ecology) was used for in vitro cultivation of the human gut microbiota (3 donors) prior to and following the addition of ivermectin to the system. These additions were performed on bioreactors which had stabilized on a background of media supplemented with either soluble or insoluble fiber or no addition controls. Data collected include 16S rRNA gene amplicon sequencing and short chain fatty acid (SCFA) concentrations.