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Data from: Impact of Ivermectin on the Gut Microbial Ecosystem

dataset
posted on 2024-06-25, 20:10 authored by Adrienne NarroweAdrienne Narrowe, LinShu Liu, Karley K. Mahalak, Jamshed T. Bobokalonov, Jenni Firrman, Johanna Lemons, Kyle Bittinger, Weiming Hu, Steven M. Jones, Ahmed M. Moustafa

The SHIME® (Simulator of the Human Intestinal Microbial Ecology) was used for in vitro cultivation of the human gut microbiota (3 donors) prior to and following the addition of ivermectin to the system. These additions were performed on bioreactors which had stabilized on a background of media supplemented with either soluble or insoluble fiber or no addition controls. Data collected include 16S rRNA gene amplicon sequencing and short chain fatty acid (SCFA) concentrations.

Funding

USDA-ARS: 8072-41000-108-000D

USDA-ARS: 0500-00093-001-11-D

History

Data contact name

Narrowe, Adrienne

Data contact email

adrienne.narrowe@usda.gov

Publisher

Ag Data Commons

Temporal Extent Start Date

2020-01-01

Temporal Extent End Date

2023-09-26

Theme

  • Non-geospatial

Geographic location - description

Data collected in Wyndmoor, PA, USA and Philadelphia, PA, USA

ISO Topic Category

  • health
  • biota

National Agricultural Library Thesaurus terms

ivermectin; intestinal microorganisms; microbial ecology; in vitro culture; bioreactors; insoluble fiber; data collection; ribosomal RNA; genes; sequence analysis; short chain fatty acids

OMB Bureau Code

  • 005:18 - Agricultural Research Service

OMB Program Code

  • 005:040 - National Research

ARS National Program Number

  • 306

ARIS Log Number

408562

Pending citation

  • No

Public Access Level

  • Public