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Co-occurrence patterns of bacterial communities and resistance genes: A comprehensive fecal microbiome and resistome study from multiple dairy cattle farms

dataset
posted on 2025-04-26, 03:58 authored by Bart C Weimer
Antimicrobial resistance (AMR) poses a critical public health threat, with rising multidrug resistance cases compromising treatment effectiveness. Knowledge about the resistome in dairy production systems remains limited, particularly regarding lactating cows. This study investigated the microbiome and resistome variations across the hospital, fresh, and mid-lactation pens on 18 conventional dairy farms in California and Ohio using shotgun metagenomic sequencing of pooled fecal samples. Findings from this study suggest that antimicrobial drug use may not be the primary driver of resistome composition in dairy cattle, highlighting the need to investigate other factors influencing AMR dynamics in livestock systems.

Funding

USDA: 2018-68003-27466

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2025-04-02

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

metagenomics; sequence analysis

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA1245445

Preferred dataset citation

It is recommended to cite the accession numbers that are assigned to data submissions, e.g. the GenBank, WGS or SRA accession numbers. If individual BioProjects need to be referenced, state that "The data have been deposited with links to BioProject accession number PRJNA1245445 in the NCBI BioProject database (https://www.ncbi.nlm.nih.gov/bioproject/)."

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