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Citrobacter rodentium strain:ATCC 51459 (DBS100) Transcriptome or Gene expression

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posted on 2024-11-23, 21:43 authored by USDA/ARS/BHNRC
Citrobacter rodentium (Cr) is a mouse pathogen that mimics many aspects of enteropathogenic Escherichia coli infections including producing attaching and effacing (A/E) lesions. Host-adapted (HA) Cr cells that are shed at the peak of infection have been reported to be hyperinfective. The exact mechanism underlying this phenomenon has remained elusive since the pathogen loses its HA ‘status’ immediately upon sub-culturing in laboratory media. We sequenced the entire transcriptome of Cr isolated from the feces of infected mice and from media grown Cr, and looked for differentially expressed genes. These results demonstrate that host-adapted Cr has a unique transcriptome that is associated with increased host transmission.

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2015-09-10

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

transcriptome; gene expression

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA295262

Preferred dataset citation

It is recommended to cite the accession numbers that are assigned to data submissions, e.g. the GenBank, WGS or SRA accession numbers. If individual BioProjects need to be referenced, state that "The data have been deposited with links to BioProject accession number PRJNA295262 in the NCBI BioProject database (https://www.ncbi.nlm.nih.gov/bioproject/)."

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