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Bos taurus breed:Holstein Transcriptome or Gene expression

dataset
posted on 2024-02-06, 23:53 authored by USDA-ARS-NADC
Johne’s disease is a chronic infection of the intestinal mucosa caused by Mycobacterium avium subspecies paratuberculosis (MAP). The events of pathogen survival, inflammation and progression to the clinical stages of infection are poorly understood. This study examines gene expression in the ileoceocal valve (ICV) of Holstein dairy cows at different stages of MAP infection. The ICV is known to be a primary site of MAP colonization and provides an ideal location to identify genes that are relevant to the progression of this disease. RNA was prepared from ICV tissues and RNA-Seq was used to compare gene transcription between clinical, subclinical, and negative control animals.

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2015-07-20

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

transcriptome; gene expression

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA290388

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