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Amblyomma maculatum Transcriptome or Gene expression

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posted on 2024-06-11, 06:56 authored by National Institute of Allergy and Infectious Diseases

Bulk RNA sequencing of R. parkeri infected and uninfected hemocytes from Amblyomma maculatum revealed 39,249 mRNA transcripts. Differential gene expression analysis revealed 17 upregulated and 35 downregulated genes with immune functions in R. parkeri infected hemocytes. Using a reverse genetic approach (RNAi), we characterized the functions of two genes, nimrod B2, and eater as unique to phagocytic hemocytes and critical for phagocytosis.

Funding

National Institute of Food and Agriculture, 2016-67030-24576

National Institute of Food and Agriculture, 2017-67017-26171

National Institutes of Health, P20GM103476

Intramural NIH HHS, Z01 AI001012

Intramural NIH HHS, ZIA AI000810

History

Data contact name

BioProject Curation Staff

Data contact email

bioprojecthelp@ncbi.nlm.nih.gov

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2022-09-09

Theme

Non-geospatial

ISO Topic Category

biota

National Agricultural Library Thesaurus terms

transcriptome; gene expression

Pending citation

Public Access Level

Public

Accession Number

PRJNA878782

Preferred dataset citation

It is recommended to cite the accession numbers that are assigned to data submissions, e.g. the GenBank, WGS or SRA accession numbers. If individual BioProjects need to be referenced, state that "The data have been deposited with links to BioProject accession number PRJNA878782 in the NCBI BioProject database (https://www.ncbi.nlm.nih.gov/bioproject/)."

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Keywords

Amblyomma maculatum eEukaryotes transcriptome

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