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16S V4 amplicon sequences from the mouse gut microbiome Raw sequence reads

dataset
posted on 2024-01-26, 23:46 authored by Montana State University
Iron is an essential nutrient for mammals and involved in multiple redox reactions essential for the survival. Currently, it is unclear whether the gut microbiome is involved in iron homeostasis or whether dietary iron levels influences microbiome composition and function. In this study, we induced anemia by feeding conventional C57Bl/6 mice a purified diet containing a very low level of iron (~4 parts per million) and found the composition of the gut microbiome to change dramatically during anemia. When inorganic iron was reintroduced into the diet some bacteria are unable to recover from an anemic whereas populations recover. These studies provide a new model of anemia-induced microbiome perturbation and add to the growing understanding of mammalian iron pools and cycling.

Funding

U.S. Department of Agriculture, Agriculture Hatch Project 1009600

National Institutes of Health, R21DK114607

History

Data contact name

BioProject Curation Staff

Publisher

National Center for Biotechnology Information

Temporal Extent Start Date

2019-08-28

Theme

  • Non-geospatial

ISO Topic Category

  • biota

National Agricultural Library Thesaurus terms

sequence analysis

Pending citation

  • No

Public Access Level

  • Public

Accession Number

PRJNA562734

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